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DOSAGE OF DORMICUM
The usual adult dose is 1-2 tablets (7.5 -15 mg). Because of the short sojourn of Midazolam in the body, DORMICUM can be taken any time of day, provided the patient is subsequently assured of at least four hours undisturbed sleep. Then there is hardly any need to fear residual effects. Owing to the rapid onset of action, DORMICUM should be taken immediately before retiring. The tablet should be swallowed whole with fluid.
SPECIAL DOSAGE INSTRUCTIONS
In elderly and debilitated patients, the recommended dose is 7.5 mg. This dosage applies also to patients with impaired liver and/or kidney function. In premedication, 2 tablets of DORMICUM should be given orally thirty to sixty minutes before the operation, unless the parenteral route is preferred.
SIDE EFFECTS OF DORMICUM
DORMICUM is well tolerated and has a broad therapeutic margin. No changes in the blood picture or in hepatic or renal function have been observed. The unusual side effects are due to the sedative effect of the drug, and are dose-dependent. They generally vanish on reduction of the dose. When therapy is continued for long period, habituation may build up in predisposed patients, as with all sleep-inducing agents, sedatives and tranquilizers. In rare cases, patients who are woken by unusual stimuli during the first two or three hours of sleep after taking the tablet may notice a loss of memory (amnesic episodes) with regard to day-to-day activities during these wake phases.
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