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GENERIC NAME: Lorazepam
BRAND NAME: Ativan
USAGE
Lorazepam is used for the administration of anxiety disorders, the short-term relief of symptoms of anxiety. The effectiveness of Lorazepam and other benzodiazepines has not been adequately studied for treatment beyond 4 months. Lorazepam is effective for insomnia, panic attacks, and is used in combination with other medications to prevent nausea and vomiting resulting from chemotherapy. Lorazepam also is administered before anesthesia and used for prevention and treatment of alcohol withdrawal.
DOSAGE
The dose of Lorazepam is tailored to the patient's needs. The usual dose for treating anxiety is 2-3 mg/day given in two or three divided doses. Insomnia is treated with 2-4 mg given at bedtime.
SIDE EFFECTS
The ordinary side effects associated with Lorazepam are sedation (15.9% of patients), dizziness (6.9% of patients), weakness, and unsteadiness. Other side effects include a feeling of depression, loss of orientation, headache, and sleep disturbance.
Like all benzodiazepines, Lorazepam can cause physical dependence. Suddenly stopping therapy after a few months of daily therapy may be associated with a feeling of loss of self-worth, agitation, and insomnia. If Lorazepam is taken continuously for longer than a few months, stopping therapy suddenly may produce seizures, tremors, muscle cramping, vomiting, and sweating.
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